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Also, virus-specific CD4+ T cells are important not only for resolving the acute infection but also for controlling latent infection, this pool of CD4+ and CD8+ T cells are constantly surveying the infected cells for markers of infection, specifically epitopes derived from TELs (Cesarman, 2011 – Decman et al., 2005 – Hislop et al., 2007 – Lang et al., 2011 – Nakanishi et al., 2009 – van Leeuwen et al., 2004 – Simon et al., 2006 – Grzimek, 2001)
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