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CntA/B is a notoriously hard enzyme to study, but once it was stabilized, we were able to gain insight into how CntA perceives its L-carnitine substrate with a 3D crystal structure model, and by studying the complete electron transfer pathway, we could see how the protein is able to turn over TMA

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Overstimulation can lead to feedback inhibition , where the hypothalamus and pituitary reduce their natural hormone production

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